1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol 3-methyl ether-d<sub>5</sub>

By Targets:	11β-HSD (2) 17β-HSD (11) 5-HT Receptor (1) Androgen Receptor (1) Apoptosis (1) Bacterial (4) Biochemical Assay Reagents (2) Calcium Channel (1) Cytochrome P450 (6) Drug Metabolite (1) Endogenous Metabolite (10) Estrogen Receptor/ERR (3) Fluorescent Dye (1) Fungal (1) GABA Receptor (2) Glucosidase (1) Isotope-Labeled Compounds (17) Na+/K+ ATPase (1) NO Synthase (2) PGE synthase (1) PI3K (1) Progesterone Receptor (5) Prostaglandin Receptor (1) Reactive Oxygen Species (1) Steroid Sulfatase (4) TRP Channel (1)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Endocrinology (9) Infection (4) Inflammation/Immunology (3) Metabolic Disease (16) Neurological Disease (6)
Click Chemistry:	Alkynes (1)

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0891S

17α-Hydroxyprogesterone-d8 17-Hydroxyprogesterone-d<sub>8sub>; 17-OHP-d<sub>8sub>	Progesterone Receptor Endogenous Metabolite	Others
17α-Hydroxyprogesterone-d₈ is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-146626S

*1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol* 3-methyl ether-d5**	Isotope-Labeled Compounds	Cancer
1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol 3-methyl ether-d₅ is the deuterium labeled 1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol 3-methyl ether[1].

HY-W703425

17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one delta-5(6)-Norethindrone	Progesterone Receptor	Endocrinology
17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one (delta-5(6)-Norethindrone), an impurity of Norethindrone, is an anabolic agent. Norethindrone is a progestin athat can be used for endometriosis research .

HY-N0347

17α-Hydroxyprogesterone acetate
17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface .

HY-151201

*Steroid sulfatase/17β-HSD1-IN-3*	Steroid Sulfatase	Cancer
Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 irreversibly inhibits hSTS activity with anIC₅₀ value of 27 nM. Steroid sulfatase/17β-HSD1-IN-3 can be used in the study of endometriosis and other estrogen-dependent diseases .

HY-151202

*Steroid sulfatase/17β-HSD1-IN-4*	Steroid Sulfatase	Cancer
Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS activity with anIC₅₀ value of 63 nM. Steroid sulfatase/17β-HSD1-IN-4 can be used in the study of endometriosis and other estrogen-dependent diseases .

HY-B0891S1

17α-Hydroxyprogesterone-13C3 17-Hydroxyprogesterone-¹³C<sub>3sub>; 17-OHP-¹³C<sub>3sub>	Progesterone Receptor Endogenous Metabolite	Others
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-107462

17α-Hydroxydigitoxigenin

Biochemical Assay Reagents Others

17α-Hydroxydigitoxigenin is an active small molecule .

17α-Hydroxydigitoxigenin	Biochemical Assay Reagents	Others
17α-Hydroxydigitoxigenin is an active small molecule .

HY-B0891R

17α-Hydroxyprogesterone (Standard) 17-Hydroxyprogesterone(Standard); 17-OHP (Standard)	Progesterone Receptor Endogenous Metabolite	Others
17α-Hydroxyprogesterone (Standard) is the analytical standard of 17α-Hydroxyprogesterone. This product is intended for research and analytical applications.

HY-141672S1

17β-Estradiol sulfate-d4 sodium 17β-Estradiol 3-sulfate-d<sub>4sub> (sodium)	GABA Receptor
17β-Estradiol sulfate-d₄ (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].

HY-113263S1

17α-Hydroxypregnenolone-13C2,d2	Endogenous Metabolite Isotope-Labeled Compounds	Others
17α-Hydroxypregnenolone- ¹³C₂,d₂ is the deuterium and ¹³C labeled 17α-Hydroxypregnenolone[1].

HY-B0742

Hydroxyprogesterone caproate 3 Publications Verification 17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate	Others	Others
Hydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid.

HY-N1605

17α-Neriifolin

Others Others

17α-Neriifolin is a compound isolated from a methylene chloride extract of the seeds of Cerbera odollam .
HY-N12341

17α-Deacetyltanghinin

Others Others

17α-Deacetyltanghinin is monoxide that can be isolated from? the airdried leaves of Cérbera odollam .
HY-N1606

17α-Thevebioside

Others Others

17α-Thevebioside is the compound isolated from air-dried leaves of Cerbera manghas and C. odollam .

17α-Neriifolin	Others	Others
17α-Neriifolin is a compound isolated from a methylene chloride extract of the seeds of Cerbera odollam .

17α-Deacetyltanghinin	Others	Others
17α-Deacetyltanghinin is monoxide that can be isolated from? the airdried leaves of Cérbera odollam .

17α-Thevebioside	Others	Others
17α-Thevebioside is the compound isolated from air-dried leaves of Cerbera manghas and C. odollam .

HY-126083

17β-Hydroxywortmannin Wortmannin-17β-ol	PI3K	Others Cancer
17β-Hydroxywortmannin (Wortmannin-17β-ol) is an orally active inhibitor for phosphatidylinositol-3-kinase (PI-3-kinase) with an IC₅₀ of 0.5 nM, suppresses the osteoclast resorption with an IC₅₀ of 10 nM . 17β-Hydroxywortmannin exhibits antitumor activity .

HY-B1643

Ethyl Vanillate

Fungal Infection

Ethyl Vanillate is a fungicidal agent. Ethyl Vanillate inhibits 17β-HSD2 with an IC₅₀ 1.3 µM .

Ethyl Vanillate	Fungal	Infection
Ethyl Vanillate is a fungicidal agent. Ethyl Vanillate inhibits *17β-HSD2* with an IC₅₀ 1.3 µM .

HY-145433

17β-HSD1-IN-1	Others	Cancer
17β-HSD1-IN-1 (Compound 1) is a highly selective *17β-HSD1* inhibitor with IC₅₀s of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively. 17β-HSD1-IN-1 can be used for the research of non-small cell lung cancer (NSCLC) .

HY-141907S

17β-Estradiol-13C3

Isotope-Labeled Compounds Others

17β-Estradiol- ¹³C₃ is the ¹³C labeled 17β-Estradiol[1].

17β-Estradiol-13C3	Isotope-Labeled Compounds	Others
17β-Estradiol- ¹³C₃ is the ¹³C labeled 17β-Estradiol[1].

HY-155534

17β-HSD10-IN-1	Endogenous Metabolite	Others
17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of **17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)** with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects .

HY-155535

17β-HSD10-IN-2	Endogenous Metabolite	Neurological Disease
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .

HY-155010

*Steroid sulfatase/17β-HSD1-IN-5*	Steroid Sulfatase	Metabolic Disease
Steroid sulfatase/17β-HSD1-IN-5 is a irreversible inhibitor of steroid sulfatase (STS) .Steroid sulfatase/17β-HSD1-IN-5 is a reversible and selective inhibitor of 7β-hydroxysteroid dehydrogenase type1 (17β-HSD1), with IC₅₀s of 43 nM and 6.2μM for 17β-HSD1 and 17β-HSD2, respectively. Steroid sulfatase/17β-HSD1-IN-5 can be used for metabolic disease (especially for endometriosis) research .

HY-151199

*Steroid sulfatase/17β-HSD1-IN-1*	Steroid Sulfatase	Endocrinology Cancer
Steroid sulfatase/17β-HSD1-IN-1 is a potent steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor with an IC₅₀ value of 28 nM for cellular human steroid sulfatase. Steroid sulfatase/17β-HSD1-IN-1 can be used to research estrogen-dependent diseases .

HY-157935

17β-HSD10-IN-3	Endogenous Metabolite	Neurological Disease
17β-HSD10-IN-3 (compound 23) is a *17β-HSD10* inhibitor with the IC₅₀ of 5.59 μM. 17β-HSD10-IN-3 shows no cell cytotoxicity toward the HEK-293 cell line up to 20 μM .

HY-B0891

17α-Hydroxyprogesterone 2 Publications Verification 17-Hydroxyprogesterone; 17-OHP
17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progesterone that serves as a chemical intermediate in the biosynthesis of other steroid hormones, including glucocorticoids, androgens, and estrogens.

HY-142798S

16-Keto 17β-Estradiol-d5 (Major)

Isotope-Labeled Compounds Others

16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].
HY-146630S

17β-Dihydroequilenin-4,16,16-d3

Isotope-Labeled Compounds

17β-Dihydroequilenin-4,16,16-d₃ is the deuterium labeled 17β-Dihydroequilenin-4,16,16[1].
HY-N12342

17β-Tanghinigenin

Others Others

17β-Tanghinigenin is a kind of glucos-3-ulosyl-thevetoside .

*16-Keto 17β-Estradiol-d5 (Major)*	Isotope-Labeled Compounds	Others
16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].

17β-Dihydroequilenin-4,16,16-d3	Isotope-Labeled Compounds
17β-Dihydroequilenin-4,16,16-d₃ is the deuterium labeled 17β-Dihydroequilenin-4,16,16[1].

17β-Tanghinigenin	Others	Others
17β-Tanghinigenin is a kind of glucos-3-ulosyl-thevetoside .

HY-146638S

*5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4*	Isotope-Labeled Compounds	Cancer
5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d₄ is the deuterium labeled 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5[1].

HY-132723S

17β-Estradiol-3-β-D-glucuronide-d3

Isotope-Labeled Compounds Others

17β-Estradiol-3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

17β-Estradiol-3-β-D-glucuronide-d3	Isotope-Labeled Compounds	Others
17β-Estradiol-3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

HY-132723AS

17β-Estradiol-3-β-D-glucuronide-d3 sodium	Isotope-Labeled Compounds	Others
17β-Estradiol-3-β-D-glucuronide-d₃ (sodium) is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

HY-W587733

17α,20β-Dihydroxy-4-pregnen-3-one

17,20β-P; 17,20β-DHP
Others Endocrinology

17α,20β-Dihydroxy-4-pregnen-3-one (17,20β-P) is a maturation-inducing steroid .

17α,20β-Dihydroxy-4-pregnen-3-one 17,20β-P; 17,20β-DHP	Others	Endocrinology
17α,20β-Dihydroxy-4-pregnen-3-one (17,20β-P) is a maturation-inducing steroid .

HY-141672

17β-Estradiol sulfate sodium 1 Publications Verification 17β-Estradiol 3-sulfate sodium	GABA Receptor	Neurological Disease
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .

HY-146734S

17β-Dihydroequilenin 3-sulfate-4,16,16-d3 sodium	Isotope-Labeled Compounds
17β-Dihydroequilenin 3-sulfate-4,16,16-d₃ (sodium) is the deuterium labeled 17β-Dihydroequilenin 3-sulfate-4,16,16.

HY-142279S

17β-Estradiol 17-acetate 3-β-D-glucuronide-d3	Isotope-Labeled Compounds	Others
17β-Estradiol 17-acetate 3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide[1].

HY-13331

Clascoterone Cortexolone 17 alpha-propionate; Cortexolone 17α-propionate; CB-03-01	Androgen Receptor	Endocrinology
Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.

HY-130046S1

16β-Hydroxy-17β-estradiol-2,4-d2

Bacterial Isotope-Labeled Compounds Others

16β-Hydroxy-17β-estradiol-2,4-d₂ is the deuterium labeled 16β-Hydroxy-17β-estradiol-2,4[1].

*16β-Hydroxy-17β-estradiol-2,4-d2*	Bacterial Isotope-Labeled Compounds	Others
16β-Hydroxy-17β-estradiol-2,4-d₂ is the deuterium labeled 16β-Hydroxy-17β-estradiol-2,4[1].

HY-146736S

17β-Dihydroequilin 3-sulfate-2,4,16,16-d4 sodium	Isotope-Labeled Compounds
17β-Dihydroequilin 3-sulfate-2,4,16,16-d₄ (sodium) is the deuterium labeled 17β-Dihydroequilin 3-sulfate-2,4,16,16.

HY-146631S

4-Hydroxy-17β-estradiol-1,2,16,16,17-d5

Isotope-Labeled Compounds

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].

*4-Hydroxy-17β-estradiol-1,2,16,16,17-d5*	Isotope-Labeled Compounds
4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].

HY-128976

*10β,17β-dihydroxyestra-1,4-dien-3-one* DHED	Estrogen Receptor/ERR	Metabolic Disease
10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) is a brain-targeting bioprecursor proagent of the main human estrogen, 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain .

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d<sub>4sub>; Ethynylestradiol-d<sub>4sub>	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118382

SCH-451659

17β-HSD Cancer

SCH-451659 is an inhibitor of 17β-hydroxysteroid dehydrogenases (17β-HSDs) for cancer research .
HY-145575

Itruvone

PH10
Others Neurological Disease

Itruvone is a intermediate of 17α-ethinylestradiol (EE2) during Fenton oxidation. Itruvone has an antidepressant effect .

SCH-451659	17β-HSD	Cancer
SCH-451659 is an inhibitor of 17β-hydroxysteroid dehydrogenases (17β-HSDs) for cancer research .

Itruvone PH10	Others	Neurological Disease
Itruvone is a intermediate of 17α-ethinylestradiol (EE2) during Fenton oxidation. Itruvone has an antidepressant effect .

HY-103394

TC HSD 21	Others	Cancer
TC HSD 21 is a potent **17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC₅₀** of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors .

HY-B0648

Medroxyprogesterone 5+ Cited Publications 17α-Hydroxy-6α-methylprogesterone; U8840	Progesterone Receptor	Endocrinology Cancer
Medroxyprogesterone (17α-Hydroxy-6α-methylprogesterone) is a synthetic human variant of progesterone that is a progesterone receptor agonist with oral activity. Medroxyprogesterone can induce cell proliferation through the PI3K/Akt signaling pathway. Medroxyprogesterone has an inhibitory effect on atherosclerosis in mice. The progesterone agonist activity of Medroxyprogesterone is less effective than Medroxyprogesterone acetate (HY-B0469) .

HY-W016604

4'-Hydroxyvalerophenone 4-Pentanoylphenol; 4-Valerylphenol	17β-HSD	Cancer
4'-Hydroxyvalerophenone (Compound 4) is an inhibitor of 17β-hydroxysteroid dehydrogenase (17β-HSD) with an IC₅₀ of 60.52 μM .

HY-W012689S

*2-Methyl-2-propylpropane-1,3-diol-d3* Dimethylolpentane-d<sub>3sub>	Isotope-Labeled Compounds	Others
2-Methyl-2-propylpropane-1,3-diol-d₃ is the deuterium labeled 2-Methyl-2-propylpropane-1,3-diol[1].

HY-N8011

*25(R)-3β,17α-Dihydroxy-5α-spirostan-6-one 3-O-α-D-rhamnopyranosyl-(1→2)-β-D-glucopyranoside*	Others	Others
25(R)-3β,17α-Dihydroxy-5α-spirostan-6-one 3-O-α-D-rhamnopyranosyl-(1→2)-β-D-glucopyranoside is a compound that can be isolated from Lilium brownii var. viridulum .

HY-N10046

ent-17-Hydroxykauran-3-one ent-Kaurane-3-oxo-17β-ol	Others	Others
ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana .

HY-70013S

Abiraterone-d4 CB-7598-d<sub>4sub>	Cytochrome P450	Cancer
Abiraterone-d₄ is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.

Cat. No.	Product Name

HY-L041

Macrocyclic Compound Library

364 compounds

Macrocycles, molecules containing 12-membered or larger rings, are receiving increased attention in small-molecule drug discovery. The reasons are several, including providing access to novel chemical space, challenging new protein targets, showing favorable ADME- and PK-properties. Macrocycles have demonstrated repeated success when addressing targets that have proved to be highly challenging for standard small-molecule drug discovery, especially in modulating macromolecular processes such as protein–protein interactions (PPI). Otherwise, the size and complexity of macrocyclic compounds make possible to ensure numerous and spatially distributed binding interactions, thereby increasing both binding affinity and selectivity.

MCE offers a unique collection of 364 macrocyclic compounds which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE Macrocyclic Compound Library is a useful tool for discovering new drugs, especially for “undruggable” targets and protein–protein interactions.

Cat. No.	Product Name	Type

HY-D0144

Resorufin methyl ether Methoxyresorufin	Chromogenic Substrates
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .

HY-D0145

7-Ethoxyresorufin 1 Publications Verification Resorufin ethyl ether	Chromogenic Substrates
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase .

HY-D1904

D-Luciferin 6'-methyl ether	Fluorescent Dyes/Probes
D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates .

HY-115749A

*(Rac)-Luciferin 6′-methyl* ether sodium** (Rac)-6′-Methoxyluciferin sodium	Fluorescent Dyes/Probes
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC₅₀ of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .

Cat. No.	Product Name	Type

HY-W127440

i-Cholesteryl methyl ether	Biochemical Assay Reagents
i-Cholesteryl methyl ether is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species	Inflammation/Immunology
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-155534

17β-HSD10-IN-1	Structural Classification Monophenols Classification of Application Fields Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of **17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)** with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects .

HY-B0891R

17α-Hydroxyprogesterone (Standard) 17-Hydroxyprogesterone(Standard); 17-OHP (Standard)	Structural Classification Classification of Application Fields Source classification Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Steroids	Progesterone Receptor Endogenous Metabolite
17α-Hydroxyprogesterone (Standard) is the analytical standard of 17α-Hydroxyprogesterone. This product is intended for research and analytical applications.

HY-N12341

17α-Deacetyltanghinin	Apocynaceae Structural Classification Cerbera odollam Gaertn. Source classification Plants Saccharides Monosaccharides	Others
17α-Deacetyltanghinin is monoxide that can be isolated from? the airdried leaves of Cérbera odollam .

HY-155535

17β-HSD10-IN-2	Structural Classification Monophenols Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .

HY-N12342

17β-Tanghinigenin	Apocynaceae Structural Classification Source classification Cerbera manghas Linn. Plants Saccharides Monosaccharides	Others
17β-Tanghinigenin is a kind of glucos-3-ulosyl-thevetoside .

HY-N8011

*25(R)-3β,17α-Dihydroxy-5α-spirostan-6-one 3-O-α-D-rhamnopyranosyl-(1→2)-β-D-glucopyranoside*	Structural Classification Liliaceae Source classification Lilium dauricum Ker-Gawl. Plants Steroids	Others
25(R)-3β,17α-Dihydroxy-5α-spirostan-6-one 3-O-α-D-rhamnopyranosyl-(1→2)-β-D-glucopyranoside is a compound that can be isolated from Lilium brownii var. viridulum .

HY-N10046

ent-17-Hydroxykauran-3-one ent-Kaurane-3-oxo-17β-ol	Structural Classification Euphorbia fischeriana Steud. Terpenoids Source classification Diterpenoids Euphorbiaceae Plants	Others
ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana .

HY-W015788

1-Phenylethane-1,2-diol Styrene Glycol	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Others
1-Phenylethane-1,2-diol is a typical benzyl diol compound. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics .

HY-N9203

Pinobanksin 5-methyl ether	Infection Structural Classification Flavanonols Flavonoids Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial
Pinobanksin 5-methyl ether can be isolated from Georgian Propolises. Pinobanksin 5-methyl ether has anti-helicobacter activity. Pinobanksin 5-methyl ether is effective inducer of CYP9Q enzyme .

HY-N9551

Eriodictyol chalcone	Structural Classification Chalcones Flavonoids Classification of Application Fields Daucus carota Linn. var. sativa Hoffm. Source classification Phenols Polyphenols Metabolic Disease Plants Umbelliferae Disease Research Fields	Cytochrome P450
Eriodictyol chalcone possesses both anti-aromatase and an anti-17β-HSD activity .

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Galinsoga parviflora Cav. Flavonoids Flavones Labiatae Source classification Plants	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-W049970

Carvacrol methyl ether	Infection Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Bacterial
Carvacrol methyl ether, a Carvacrol analog, can be isolated from plant volatile oil. Carvacrol methyl ether exhibits antibacterial activity .

HY-B1100

Estradiol cypionate Maximum Cited Publications 9 Publications Verification	Classification of Application Fields Disease Research Fields Cancer	Estrogen Receptor/ERR Apoptosis
Estradiol cypionate is the 17β-cypionate ester of Estradiol, which inhibits ET-1 synthesis by acting on estrogen receptors .

HY-136933

Gitoxin	Cardiovascular Disease Digitalis purpurea Linn. Classification of Application Fields Source classification Scrophulariaceae Plants Disease Research Fields Steroids	Na+/K+ ATPase
Gitoxin, a Na ⁺/K ⁺-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably .

HY-N2411

Geissoschizine methyl ether	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Structural Classification Source classification Rubiaceae Plants Indole Alkaloids	5-HT Receptor
Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT_1A receptor agonist .

HY-N11000

Heteropeucenin 7-methyl ether	Structural Classification Flavonoids Source classification Rutaceae Harrisonia perforata (Blanco) Merr. Plants Other Flavonoids	Others
Heteropeucenin 7-methyl ether is a chromone that can be found in Harrisonia perforata .

HY-N12596

Uralenol-3-methyl ether	Structural Classification Flavonoids Flavones Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Others
Uralenol-3-methyl ether is a flavonol which can be extracted from Daphne giraldii .

HY-W663232

Anthragallol-2-methyl ether	Quinones Structural Classification Anthraquinones Source classification Rubiaceae Morinda citrifolia Linn. Plants	Others
Anthragallol-2-methyl ether (compound 4) can be isolated from the fruits of Morinda citrifolia .

HY-124489

2-Hydroxyestradiol	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity .

HY-130049

Lucidin ω-ethyl ether	Quinones Structural Classification Anthraquinones Source classification Rubiaceae Plants Prismatomeris filamentosa Craib	Bacterial
Lucidin ω-ethyl ether (compound 17) is an anthraquinone metabolite isolated from the root part of Prismatomeris filamentosa with some antibacterial activity against Gram-positive and Gram-negative bacteria .

HY-W667667

5-Hydroxyalizarin 1-methyl ether	Quinones Structural Classification Anthraquinones Source classification Rubiaceae Plants	Others
5-Hydroxyalizarin 1-methyl ether is a quinone compound isolated from Hymenodictyon excelsum .

HY-N8450

3-Acetylpinobanksin-7-methyl ether	Structural Classification Flavonoids Flavones Source classification Alpinia japonica (Thunb.) Miq. Plants Zingiberaceae	Others
3-Acetylpinobanksin-7-methyl ether is a natural product that can be isolated from propolis .

HY-N9961

2-Hydroxyl emodin-1-methyl ether	Quinones Structural Classification Cassia obtusifolia L. Anthraquinones Source classification Caesalpiniaceae Plants	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N10994

Peucenin 7-O-methyl ether	Structural Classification Flavonoids Source classification Rosaceae Plants Other Flavonoids Rosa rugosa Thunb.	Others
Peucenin 7-O-methyl ether is a natural product that can be isolated from the flowers of Rosa rugosa .

HY-116330

Hyperforin	Structural Classification Anti-inflammation/Immunoregulatory Antibiotics Source classification Guttiferae Hyperlcurn perforatum L. Disease Research Plants Anticancer	Calcium Channel TRP Channel
Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca ²⁺ levels by activating Ca ²⁺-conducting non-selective canonical TRPC6 channels. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model .

HY-N9134

5-O-Methylgenistein Isoprunetin	Structural Classification Flavonoids Leguminosae Source classification Maackia amurensis Rupr. et Maxim. Plants Isoflavones	Glucosidase
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast .

Species:	Human (18) E.coli (1)
Tag:	GFP (4) His (17) SUMO (1) Strep (3) Tag Free (1) Myc (2) Trx (1)
Source:	HEK293 (6) E. coli Cell-free (4) P. pastoris (1) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P76975

	HSD17B14 Protein, Human (HEK293, His) 17-beta-hydroxysteroid dehydrogenase 14; 17-beta-HSD 14; DHRS10; SDR3; SDR47C1	Human	HEK293
	HSD17B14 protein, with NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity, converts oestradiol to oestrone. Its enzymatic activity extends to both oestradiol and 5-androstene-3-beta,17-beta-diol in vitro, although the physiological substrate remains unidentified. HSD17B14 Protein, Human (HEK293, His) is the recombinant human-derived HSD17B14 protein, expressed by HEK293 , with C-His labeled tag. The total length of HSD17B14 Protein, Human (HEK293, His) is 270 a.a., with molecular weight of ~29.8 KDa.

HY-P71839

	HSD17B13 Protein, Human (P.pastoris, His-Myc) HSD17B13; SCDR9; SDR16C3; HMFN0376; 17-beta-hydroxysteroid dehydrogenase 13	Human	P. pastoris
	HSD17B13 Protein plays a pivotal role in hepatic lipid metabolism, actively contributing to the oxidation of diverse lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4. Demonstrating versatile catalytic activity in vitro, HSD17B13, notably, exhibits retinol/retinal dehydrogenase activity, emphasizing its potential impact on crucial pathways associated with lipid processing and metabolism. HSD17B13 Protein, Human (P.pastoris, His-Myc) is the recombinant human-derived HSD17B13 protein, expressed by P. pastoris , with N-His, C-Myc labeled tag. The total length of HSD17B13 Protein, Human (P.pastoris, His-Myc) is 281 a.a., with molecular weight of ~34.8 kDa.

HY-P701834

	hERG Protein, Human (HEK293, GFP, His) KCNH2; Potassium voltage-gated channel subfamily H member 2; Eag homolog; ether-a-go-go-related gene potassium channel 1; ERG-1; Eag-related protein 1; ether-a-go-go-related protein 1; H-ERG; hERG-1; hERG1; Voltage-gated potassium channel subunit Kv11.1	Human	HEK293
	The hERG protein is the α subunit of voltage-gated potassium channels and is critical for mediating cardiac delayed rectifier potassium current (IKr). It lacks individual channel activity but dynamically affects properties by forming heterotetramers with other isoforms. hERG Protein, Human (HEK293, GFP, His) is the recombinant human-derived hERG protein, expressed by HEK293 , with C-10*His, C-GFP labeled tag. ,

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P70366

	MeCP2 Protein, Human (HEK293, His) rHuMethyl-CpG-binding protein 2/MECP2, His; Methyl-CpG-binding protein 2; MECP2; MeCp-2 protein	Human	HEK293
	The MeCP2 protein is a chromosome binder that specifically binds to methylated DNA independent of flanking sequences. MeCP2 Protein, Human (HEK293, His) is the recombinant human-derived MeCP2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MeCP2 Protein, Human (HEK293, His) is 486 a.a., with molecular weight of ~90.0 kDa.

HY-P702197

	ABCD3 Protein, Human (Cell-Free, His) ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70	Human	E. coli Cell-free
	ABCD3 is a member of the ATP-binding cassette (ABC) family. ABCD3 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD3 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD3 Protein, Human (Cell-Free, His) is 659 a.a., with molecular weight of 81.5 kDa.

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P72012

	ABCD1 Protein, Human (Cell-Free, His) ABC42; Abcd1; ABCD1_HUMAN; Adrenoleukodystrophy protein; ALD; Aldgh; ALDP; AMN; ATP binding cassette; sub family D ALD; ; member 1; ATP-binding cassette sub-family D member 1; OTTHUMP00000025960; OTTMUSP00000019283; RGD1562128; RP23 373N8.2; X linked adrenoleukodystrophy ALD; gene homolog	Human	E. coli Cell-free
	ABCD1, Human (His) is one of the four ATP-binding cassette (ABC) proteins in subfamily D. Dysfunction of ABCD1 causes neurodegenerative disorder X-linked adrenoleukodystrophy (X-ALD).

HY-P702196

	ABCD2 Protein, Human (Cell-Free, His) ATP-binding cassette sub-family D member 2; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; hALDR	Human	E. coli Cell-free
	ABCD2 protein is an ATP-dependent transporter in the ABC family that promotes the transport of very long chain fatty acids (VLCFA)-CoA into peroxisomes and exhibits fatty acyl-CoA thioesterase (ACOT) and ATPase activities. Its substrate specificity overlaps with ABCD1, including a clear preference for shorter VLCFA (C22:0) and polyunsaturated fatty acids (PUFA) such as C22:6-CoA and C24:6-CoA. ABCD2 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD2 Protein, Human (Cell-Free, His) is 740 a.a., with molecular weight of 89.3 kDa.

HY-P72213

	GRIN1 Protein, Human (His) GluN1; Glutamate [NMDA] receptor subunit zeta-1; Glutamate receptor ionotropic N methyl D aspartate 1; glutamate receptor ionotropic, NMDA 1; Grin1; MRD8	Human	E. coli
	The GRIN1 protein is a component of the NMDA receptor complex that forms heterotetrameric ligand-gated ion channels with high calcium permeability. GRIN1 Protein, Human (His) is the recombinant human-derived GRIN1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GRIN1 Protein, Human (His) is 541 a.a., with molecular weight of ~64.6 kDa.

HY-P71457

	Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) dxr; ispC; yaeM; b0173; JW01681-deoxy-D-xylulose 5-phosphate reductoisomerase; DXP reductoisomerase; EC 1.1.1.267; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase	E.coli	E. coli
	Dxr/DXP Reductoisomerase is pivotal in isoprenoid biosynthesis, catalyzing the rearrangement and reduction of DXP to yield MEP. This step is critical in forming isoprenoid precursors, essential for cellular processes and metabolite synthesis. The enzyme's activity emphasizes its significance in regulating isoprenoid biosynthesis and cellular functions. Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) is the recombinant E. coli-derived Dxr/DXP reductoisomerase protein, expressed by E. coli , with C-Myc, N-10*His labeled tag. The total length of Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) is 398 a.a., with molecular weight of ~48.4 kDa.

HY-P72215

	GSTP1 Protein, Human (His) Deafness; Deafness X-linked 7; DFN7; FAEES3; Fatty Acid ethyl Ester Synthase III ; Glutathione S Transferase 3; Glutathione S Transferase Pi; Glutathione S-transferase P; Glutathione S-transferase pi 1; GST class-pi; GST3; GSTP; Gstp1; GSTP1-1; GSTP1_HUMAN; PI; X linked 7	Human	E. coli
	The GSTP1 protein is critical for binding reduced glutathione to a variety of hydrophobic electrophiles, actively forming glutathione conjugates of PGA2 and PGJ2. Documented studies highlight its involvement in hepoxilin regioisomer synthesis, emphasizing the versatility of GSTP1 in processing substrates. GSTP1 Protein, Human (His) is the recombinant human-derived GSTP1 protein, expressed by E. coli , with N-10*His labeled tag. The total length of GSTP1 Protein, Human (His) is 209 a.a., with molecular weight of ~25 kDa.

HY-P702195

	ABCB8 Protein, Human (Cell-Free, His, SUMO) Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR	Human	E. coli Cell-free
	ABCB8 is the ATP-binding subunit of mitochondrial potassium channels and cooperates with CCDC51/MITOK to form mitoK (ATP) channels in the inner mitochondrial membrane. This complex promotes ATP-dependent potassium currents. ABCB8 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ABCB8 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag. The total length of ABCB8 Protein, Human (Cell-Free, His, SUMO) is 656 a.a., with molecular weight of 87 kDa.

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Human (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Human (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q, , , , mutation. The total length of bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P701887

	FTO Protein, Human FTO; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO	Human	E. coli
	FTO protein is an RNA demethylase that regulates fat mass, lipogenesis, and energy homeostasis by targeting N(6)-methyladenosine in mRNA. It also demethylates m6A in U6 snRNA and m6A(m) in 5'-cap, affecting mRNA stability. FTO Protein, Human is the recombinant human-derived FTO protein, expressed by E. coli , with tag free. The total length of FTO Protein, Human is 474 a.a., .

HY-P701888

	FTO Protein, Human (His) FTO; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO	Human	E. coli
	FTO protein is an RNA demethylase that regulates fat mass, lipogenesis, and energy homeostasis by targeting N(6)-methyladenosine in mRNA. It also demethylates m6A in U6 snRNA and m6A(m) in 5'-cap, affecting mRNA stability. FTO Protein, Human (His) is the recombinant human-derived FTO protein, expressed by E. coli , with N-6*His labeled tag. The total length of FTO Protein, Human (His) is 474 a.a., .

Cat. No.	Product Name	Chemical Structure

HY-B0891S

17α-Hydroxyprogesterone-d8
17α-Hydroxyprogesterone-d₈ is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-141672S1

17β-Estradiol sulfate-d4 sodium
17β-Estradiol sulfate-d₄ (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].

HY-146626S

*1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol* 3-methyl ether-d5**
1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol 3-methyl ether-d₅ is the deuterium labeled 1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol 3-methyl ether[1].

HY-B0891S1

17α-Hydroxyprogesterone-13C3
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-113263S1

17α-Hydroxypregnenolone-13C2,d2

17α-Hydroxypregnenolone- ¹³C₂,d₂ is the deuterium and ¹³C labeled 17α-Hydroxypregnenolone[1].
HY-141907S

17β-Estradiol-13C3

17β-Estradiol- ¹³C₃ is the ¹³C labeled 17β-Estradiol[1].
HY-142798S

16-Keto 17β-Estradiol-d5 (Major)

16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].
HY-146630S

17β-Dihydroequilenin-4,16,16-d3

17β-Dihydroequilenin-4,16,16-d₃ is the deuterium labeled 17β-Dihydroequilenin-4,16,16[1].
HY-146638S

5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4

5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d₄ is the deuterium labeled 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5[1].
HY-132723S

17β-Estradiol-3-β-D-glucuronide-d3

17β-Estradiol-3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].
HY-132723AS

17β-Estradiol-3-β-D-glucuronide-d3 sodium

17β-Estradiol-3-β-D-glucuronide-d₃ (sodium) is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].
HY-146734S

17β-Dihydroequilenin 3-sulfate-4,16,16-d3 sodium

17β-Dihydroequilenin 3-sulfate-4,16,16-d₃ (sodium) is the deuterium labeled 17β-Dihydroequilenin 3-sulfate-4,16,16.
HY-142279S

17β-Estradiol 17-acetate 3-β-D-glucuronide-d3

17β-Estradiol 17-acetate 3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide[1].
HY-130046S1

16β-Hydroxy-17β-estradiol-2,4-d2

16β-Hydroxy-17β-estradiol-2,4-d₂ is the deuterium labeled 16β-Hydroxy-17β-estradiol-2,4[1].
HY-146736S

17β-Dihydroequilin 3-sulfate-2,4,16,16-d4 sodium

17β-Dihydroequilin 3-sulfate-2,4,16,16-d₄ (sodium) is the deuterium labeled 17β-Dihydroequilin 3-sulfate-2,4,16,16.
HY-146631S

4-Hydroxy-17β-estradiol-1,2,16,16,17-d5

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].

HY-B0216S

Ethynyl Estradiol-d4

Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W012689S

2-Methyl-2-propylpropane-1,3-diol-d3

2-Methyl-2-propylpropane-1,3-diol-d₃ is the deuterium labeled 2-Methyl-2-propylpropane-1,3-diol[1].

HY-70013S

Abiraterone-d4
Abiraterone-d₄ is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.

HY-W585866S

Alternariol, methyl ether-13C15

Alternariol, methyl ether- ¹³C15 is a ¹³C labeled Alternariol, methyl ether.

HY-D0145S

7-Ethoxyresorufin-d5
7-Ethoxyresorufin-d₅ is deuterium labeled 7-Ethoxyresorufin. 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2].

HY-B0683S

Limaprost-d3
Limaprost-d₃ (17α,20-dimethyl-δ2-PGE1-d3) is the deuterium labeled Limaprost. Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research[1][2].

HY-150708S

Ethyl 2-hydroxy-2-methyl-3-oxobutanoate-13C

Ethyl 2-hydroxy-2-methyl-3-oxobutanoate- ¹³C is the ¹³C labeled Ethyl 2-hydroxy-2-methyl-3-oxobutanoate[1].

Cat. No.	Product Name	Application	Reactivity

HY-P83598

ERAB Antibody (YA3343) HSD17B10; ERAB; HADH2; MRPP2; SCHAD; XH98G2; 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P83303

HSD17B1 Antibody (YA3048)

hydroxysteroid (17-beta) dehydrogenase 1; HSD17; EDHB17; EDH17B2; SDR28C1
WB, IHC-F, IHC-P, ICC/IF, IP Human

HY-P80171

*Histone H3 (di methyl* K9) Antibody**	WB, ICC/IF, IHC-P	Human, Mouse, Rat
Histone H3 (di methyl K9) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Histone H3 (di methyl K9). It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80172

*Histone H3 (mono methyl* K18) Antibody**	WB, ICC/IF, IHC-P	Human, Mouse
Histone H3 (mono methyl K18) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Histone H3 (mono methyl K18). It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P80173

*Histone H3 (mono methyl* K36)Antibody**	WB, ICC/IF	Human, Mouse
Histone H3 (mono methyl K36)Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Histone H3 (mono methyl K36). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse.

HY-P80174

*Histone H3 (mono methyl* R2)Antibody**	WB, ICC/IF	Human, Mouse
Histone H3 (mono methyl R2)Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Histone H3 (mono methyl R2). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse.

HY-P80181

*Histone H4 (tri methyl* K20) Antibody**	WB, IHC-P	Human, Mouse
Histone H4 (tri methyl K20) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 11 kDa, targeting to Histone H4 (tri methyl K20). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P81950

MBD3 Antibody (YA1695)

MBD3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
WB, ICC/IF, IP, FC Human, Mouse, Rat

HY-P80165

*Histone H2B (mono methyl* R79) Antibody**	WB, ICC/IF, IHC-P	Human, Mouse
Histone H2B (mono methyl R79) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 14 kDa, targeting to Histone H2B(mono methyl R79). It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P80175

*Histone H3 (mono+di+tri methyl* K79) Antibody**	WB, IHC-P	Human, Mouse, Rat
Histone H3 (mono+di+tri methyl K79) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Histone H3 (mono+di+tri methyl K79). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80527

ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80772

P Glycoprotein Antibody p-pg; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

MRP2/ABCC2 Antibody multidrug resistance-associated protein2; ABC30; ABCC2; ATP binding cassette sub family C (CFTR/MRP) member 2; ATP binding cassette subfamily C member 2; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; CMOAT; CMOAT1; cMRP; DJS; KIAA1010; MRP 2; MRP-2; MRP2; Multidrug resistance associated protein 2; MRP2_HUMAN; ATP-binding cassette sub-family C member 2; Multidrug resistance-associated protein 2.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat,
MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 polyclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, background without labeling.

HY-P80176

*Histone H3 (tri methyl* K9) Antibody** H3K9me3; H3 histone family member E pseudogene; H3 histone family, memberA; H3/A; H31_HUMAN; H3F3; H3FA; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST3H3; histone 1, H3a; Histone cluster 1, H3a; Histone H3 3 pseudogene; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; HistoneH3/l; H3K9me2; HistoneH3(trimethylK9)	WB, ICC, IHC-P	Human, Mouse, Rat
Histone H3 (tri methyl K9) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 15 kDa, targeting to Histone H3 (tri methyl K9). It can be used for WB,ICC,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

Cat. No.	Product Name		Classification

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d<sub>4sub>; Ethynylestradiol-d<sub>4sub>		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.


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Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

1,3,5(10)-Estratriene-17α-ethyl-3,17β-diol 3-methyl ether-d<sub>5</sub>

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
Products